Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9755272 | 1.00 | SLC22A1 (0.62) | SLC22A1CYP3A4SLC5A7DNM1SLC22A2 | |
| SCHEMBL2138636 | 0.97 | SLC22A1 (0.67) | SLC22A1CYP3A4SLC5A7DNM1SLC22A2 | |
| SCHEMBL992673 | 0.97 | SLC22A1 (0.67) | SLC22A1CYP3A4SLC5A7DNM1SLC22A2 | |
| SCHEMBL14839961 | 0.97 | SLC22A1 (0.67) | SLC22A1CYP3A4SLC5A7DNM1SLC22A2 | |
| Water SCHEMBL25183170 | 0.94 | SLC22A1 (0.62) | SLC22A1CYP3A4SLC5A7DNM1SLC22A2 | |
| Water SCHEMBL597350 | 0.94 | SLC22A1 (0.62) | SLC22A1CYP3A4SLC5A7DNM1SLC22A2 | |
| Water SCHEMBL3308149 | 0.94 | SLC22A1 (0.62) | SLC22A1CYP3A4SLC5A7DNM1SLC22A2 | |
| Fluoride Ion SCHEMBL17870609 | 0.94 | SLC22A1 (0.62) | SLC22A1CYP3A4SLC5A7DNM1SLC22A2 | |
| Water SCHEMBL27424443 | 0.94 | SLC22A1 (0.62) | SLC22A1CYP3A4SLC5A7DNM1SLC22A2 | |
| Bromide SCHEMBL18954325 | 0.94 | SLC22A1 (0.62) | SLC22A1CYP3A4DNM1SLC22A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6527932-B1 | In an electrodialysis apparatus comprising one or more cell units, each cell unit comprising a bipolar membrane and an anion-selective membrane | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-04 | — | — | US | disclosed |