SCHEMBL7156382

SCHEMBL7156382

COC1=CC(C)(N)C(c2ccccc2)C=C1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 7/20 0.37
MAOA P21397 7/20 0.37
MAOB P27338 7/20 0.37
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1153469 0.68 KDM1A (0.44) KDM1AMAOAMAOB
SCHEMBL23396586 0.66 KDM1A (0.37) KDM1AMAOAMAOB
SCHEMBL11411676 0.62
SCHEMBL22875681 0.61 KCNA5 (0.32)
SCHEMBL24770458 0.59 KDM1A (0.35) KDM1AMAOAMAOB
SCHEMBL4328899 0.59 MAOA (0.44) KDM1AMAOAMAOB
SCHEMBL2653461 0.58 CHRNA7 (0.30) KDM1AMAOAMAOB
SCHEMBL353062 0.58 KDM1A (0.44) KDM1AMAOAMAOB
SCHEMBL20751817 0.57 KDM1A (0.39) KDM1AMAOAMAOB
SCHEMBL8077336 0.56 KDM1A (0.38) KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030138720-A1 Multicolor heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-07-24 US disclosed