Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | IDUA | P35475 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 3/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15151 | 0.94 | IDUA (0.36) | IDUAGUSBCA1CA9TSHR | |
| SCHEMBL15210146 | 0.94 | IDUA (0.36) | IDUAGUSBCA1CA9TSHR | |
| SCHEMBL9846802 | 0.81 | IDUA (0.39) | IDUAGUSBCA1CA9TSHR | |
| SCHEMBL9114040 | 0.76 | CA1 (0.40) | CA1CA9TSHRPRKCAKMT2A | |
| SCHEMBL2048950 | 0.70 | PRKCA (0.39) | CA1CA9PRKCA | |
| SCHEMBL22921248 | 0.70 | CA1 (0.41) | CA1CA9PRKCA | |
| SCHEMBL5585129 | 0.70 | CA1 (0.41) | CA1CA9PRKCA | |
| SCHEMBL1686987 | 0.70 | SLC6A3 (0.46) | TP53CA1KMT2A | |
| SCHEMBL24602753 | 0.69 | CA1 (0.42) | CA1CA9TSHRACEPRKCA | |
| SCHEMBL5492523 | 0.69 | CA1 (0.42) | CA1CA9TSHRACEPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696612-B1 | Biodegradable foamed articles and process for the preparation thereof | NOVAMONT SPA (IT) | 2003-10-08 | — | — | EP | disclosed |
| US-5801207-A | PROTECTIVE PACKAGING | NOVAMONT S.P.A. (IT) | 1998-09-01 | — | — | US | disclosed |
| US-5589518-A | PACKAGING | NOVAMONT S.P.A. (IT) | 1996-12-31 | — | — | US | disclosed |
| EP-0696612-A2 | Biodegradable foamed articles and process for the preparation thereof | NOVAMONT S.p.A. (IT) | 1996-02-14 | — | — | EP | disclosed |