Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620234 | 0.79 | ALDH1A1 (0.43) | SLC6A3ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL4923062 | 0.77 | MEN1 (0.43) | SLC6A3ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL15846301 | 0.76 | SLC6A3 (0.70) | SLC6A3KDM4EHPGDMAPTLMNA | |
| SCHEMBL15210146 | 0.74 | IDUA (0.36) | KDM4EL3MBTL1CA1LMNAMCL1 | |
| SCHEMBL15151 | 0.74 | IDUA (0.36) | KDM4EL3MBTL1CA1LMNAMCL1 | |
| SCHEMBL69127 | 0.72 | HTR1E (0.65) | SLC6A3TP53MAPTLMNAMEN1 | |
| SCHEMBL28622389 | 0.72 | HTR1E (0.65) | SLC6A3TP53MAPTLMNAMEN1 | |
| SCHEMBL12531975 | 0.71 | HTR1E (0.63) | SLC6A3TP53MAPTLMNAMEN1 | |
| SCHEMBL67219 | 0.71 | HTR1E (0.63) | SLC6A3TP53MAPTLMNAMEN1 | |
| SCHEMBL8373014 | 0.70 | EPHX1 (0.40) | KDM4EL3MBTL1CA1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047486-A1 | BIODEGRADABLE THERMORESPONSIVE HYDROGELS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2011-04-28 | — | — | WO | claimed |
| EP-2730604-B1 | FUNCTIONALIZED CAPROLACTONE MONOMERS USEFUL FOR MAKING POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | UNIV ALBERTA (CA) | 2018-10-24 | — | — | EP | disclosed |
| US-9139553-B2 | Poly(ethylene oxide)-block-poly(ester) block copolymers | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2015-09-22 | — | — | US | disclosed |
| EP-1994081-B1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | UNIV ALBERTA (CA) | 2014-05-21 | — | — | EP | disclosed |
| EP-2730604-A2 | Functionalized caprolactone monomers useful for making poly(ethylene oxide)-block-poly(ester) block copolymers | The Governors of the University of Alberta (CA) | 2014-05-14 | — | — | EP | disclosed |
| US-20130116428-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2013-05-09 | — | — | US | disclosed |
| US-8309515-B2 | Poly(ethylene oxide)-block-poly(ester) block copolymers | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-11-13 | — | — | US | disclosed |
| WO-2011047486-A1 | BIODEGRADABLE THERMORESPONSIVE HYDROGELS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2011-04-28 | — | — | WO | disclosed |
| US-20100137206-A1 | NOVEL LIGAND GUIDED BLOCK COPOLYMERS FOR TARGETED DRUG DELIVERY | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-06-03 | — | — | US | disclosed |
| US-20100069295-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-03-18 | — | — | US | disclosed |
| EP-1994081-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | The Governors of the University of Alberta (CA) | 2008-11-26 | — | — | EP | disclosed |
| WO-2008071009-A1 | NOVEL LIGAND GUIDED BLOCK COPOLYMERS FOR TARGETED DRUG DELIVERY | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2008-06-19 | — | — | WO | disclosed |
| WO-2007106997-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069295-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | EBPL, ELOB, DCLRE1B | SLC6A3 4842/4885ALDH1A1 4765/4885KDM4E 2938/4885 |
| US-20130116428-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | EBPL, ELOB, DCLRE1B | SLC6A3 4842/4885ALDH1A1 4765/4885KDM4E 2938/4885 |
| US-20100137206-A1 | NOVEL LIGAND GUIDED BLOCK COPOLYMERS FOR TARGETED DRUG DELIVERY | EBPL, EDNRB, BMPR1B | SLC6A3 4814/4885ALDH1A1 4782/4885KDM4E 4042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.