SCHEMBL7157148

SCHEMBL7157148

Nc1ccc(Oc2ccc(-c3c4ccccc4c(-c4ccc(Oc5ccc(C(=O)O)cc5)cc4)c4ccccc34)cc2)cc1O.Nc1ccccc1OC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 2/20 0.40
SRD5A2 P31213 3/20 0.39
TTR P02766 1/20 0.38
PARP15 Q460N3 1/20 0.36
PARP10 Q53GL7 1/20 0.36
IP6K1 Q92551 1/20 0.36
IP6K3 Q96PC2 1/20 0.36
IP6K2 Q9UHH9 1/20 0.36
AKR1C3 P42330 1/20 0.36
PTGES O14684 1/20 0.36
ALOX5 P09917 1/20 0.36
CAMKK2 Q96RR4 1/20 0.36
BTK Q06187 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
EGFR P00533 1/20 0.35
POLB P06746 1/20 0.34
IKBKB O14920 1/20 0.34
BRAF P15056 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6894961 0.90 SRD5A2 (0.47) FEN1SRD5A2TTRPARP15PARP10
SCHEMBL7062869 0.81 TTR (0.39) FEN1SRD5A2TTRCAMKK2BTK
SCHEMBL6896881 0.80 ALOX15 (0.46) ALOX5POLB
SCHEMBL7654088 0.78 PARP10 (0.58) SRD5A2TTRPARP15PARP10AKR1C3
SCHEMBL8371687 0.76 LMNA (0.38) FEN1SRD5A2TTRRXRARXRB
SCHEMBL8374929 0.76 FEN1 (0.36) FEN1TTRRXRA
SCHEMBL8373636 0.72 MMP2 (0.56) SRD5A2TTRPARP15PARP10AKR1C3
Biphenyl SCHEMBL3476095 0.71 MEN1 (0.52) ALOX5IKBKB
SCHEMBL6856538 0.70 NCOA1 (0.55) FEN1IKBKBBRAF
SCHEMBL31037423 0.70 SRD5A2 (0.53) SRD5A2TTRPARP15PARP10IP6K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189974-B1 POLYBENZOXAZOLE PRECURSORS INFINEON TECHNOLOGIES AG (DE) 2003-05-21 EP disclosed