Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.37 |
| ▸ | IKBKB | O14920 | 3/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894991 | 0.91 | LOXL2 (0.43) | TTRFEN1METAXLMERTK | |
| SCHEMBL7157148 | 0.81 | FEN1 (0.40) | TTRFEN1IKBKBRXRACAMKK2 | |
| SCHEMBL6895185 | 0.80 | KDR (0.40) | METPDGFRAKDRTLR4GAA | |
| SCHEMBL8374929 | 0.76 | FEN1 (0.36) | TTRFEN1MIFRXRA | |
| SCHEMBL8371687 | 0.74 | LMNA (0.38) | TTRFEN1RXRASRD5A2 | |
| SCHEMBL7654088 | 0.73 | PARP10 (0.58) | TTRRXRASRD5A2 | |
| Protocatechuic Acid SCHEMBL5459242 | 0.70 | TTR (0.56) | TTRIKBKBSRD5A2PYGLTLR4 | |
| SCHEMBL6894961 | 0.69 | SRD5A2 (0.47) | TTRFEN1RXRAEGFRBTK | |
| SCHEMBL8373636 | 0.67 | MMP2 (0.56) | TTRRXRASRD5A2 | |
| SCHEMBL4989575 | 0.67 | LTA4H (0.42) | PDGFRALOXL2KITKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189974-B1 | POLYBENZOXAZOLE PRECURSORS | INFINEON TECHNOLOGIES AG (DE) | 2003-05-21 | — | — | EP | disclosed |
| EP-1189974-A1 | POLYBENZOXAZOLE PRECURSORS | Infineon Technologies AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001066619-A1 | POLYBENZOXAZOLE PRECURSORS | INFINEON TECHNOLOGIES AG (DE) | 2001-09-13 | — | — | WO | disclosed |