Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.51 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298124 | 0.84 | FOLH1 (0.57) | FOLH1PRSS1F10PRSS2PRSS3 | |
| SCHEMBL6846002 | 0.82 | FOLH1 (0.62) | FOLH1PRSS1F10PRSS2PRSS3 | |
| SCHEMBL202409 | 0.79 | SLC7A5 (0.65) | PRSS1PRSS2PRSS3LOXL2 | |
| SCHEMBL288337 | 0.79 | SLC7A5 (0.65) | PRSS1PRSS2PRSS3LOXL2 | |
| SCHEMBL202408 | 0.79 | SLC7A5 (0.65) | PRSS1PRSS2PRSS3LOXL2 | |
| SCHEMBL31538733 | 0.79 | SLC7A5 (0.65) | PRSS1PRSS2PRSS3LOXL2 | |
| SCHEMBL3928753 | 0.77 | CYP1A2 (0.70) | FOLH1ANPEPRNPEPDNPEP | |
| SCHEMBL15893668 | 0.77 | PRSS1 (0.55) | FOLH1PRSS1F10PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL5274210 | 0.76 | PRSS1 (0.54) | FOLH1PRSS1F10PRSS2PRSS3 | |
| SCHEMBL18049406 | 0.74 | SLC7A5 (0.59) | PRSS1PRSS2PRSS3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | claimed |
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | APOB, F12, SERPINB1 | FOLH1 4522/4885PRSS1 34/4885F10 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.