Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 5/20 | 0.79 |
| ▸ | ESR1 | P03372 | 3/20 | 0.70 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.66 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.66 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.66 |
| ▸ | TYR | P14679 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163576 | 0.95 | SERPINE1 (0.77) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7775753 | 0.89 | SERPINE1 (1.00) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13287172 | 0.89 | SERPINE1 (0.92) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL28100061 | 0.87 | SERPINE1 (0.89) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13286951 | 0.87 | SERPINE1 (0.89) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL24871867 | 0.87 | SERPINE1 (0.89) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL27797541 | 0.87 | SERPINE1 (0.89) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL2791373 | 0.85 | SERPINE1 (1.00) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL28384704 | 0.84 | SERPINE1 (0.82) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL22660351 | 0.84 | CA12 (0.56) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1433297-A | Topical compositions comprising protected functional thiols | PROCTER & GAMBLE (US) | 2003-07-30 | — | — | CN | disclosed |
| US-6544499-B1 | Polysiloxane or silicone resin, a linker, and a molecular hook for treating amino acid based substrates; hair care | THE PROCTER & GAMBLE COMPANY | 2003-04-08 | — | — | US | disclosed |
| US-6495125-B2 | MAY BE USED IN HAIR CARE, TEXTILE CARE, COSMETICS, ORAL CARE FORMULATIONS, SKIN, NAIL, LAUNDRY, ACNE CARE FORMULATIONS | THE PROCTER & GAMBLE COMPANY | 2002-12-17 | — | — | US | disclosed |
| US-20020012639-A1 | May be used in hair care, textile care, cosmetics, oral care formulations, skin, nail, laundry, acne care formulations | PROCTER & GAMBLE COMPANY, THE | 2002-01-31 | — | — | US | disclosed |
| EP-1143916-A2 | TOPICAL COMPOSITIONS COMPRISING PROTECTED FUNCTIONAL THIOLS | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000040210-A2 | TOPICAL COMPOSITIONS COMPRISING PROTECTED FUNCTIONAL THIOLS | THE PROCTER & GAMBLE COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020012639-A1 | May be used in hair care, textile care, cosmetics, oral care formulations, skin, nail, laundry, acne care formulations | SCLY, TST, SRR | SERPINE1 1494/4885ESR1 2345/4885AKR1C4 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.