Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21945012 | 0.88 | ALDH1A1 (0.56) | ALDH1A1MAPTMAOBHSD17B1HSD17B2 | |
| SCHEMBL16398809 | 0.88 | ALDH1A1 (0.63) | ALDH1A1MAPTMAOBHSD17B1HSD17B2 | |
| SCHEMBL25221815 | 0.86 | ALDH1A1 (0.63) | ALDH1A1CSNK1DMAPTMAOBFSCN1 | |
| SCHEMBL30039055 | 0.86 | ALDH1A1 (0.63) | ALDH1A1CSNK1DMAPTMAOBFSCN1 | |
| SCHEMBL18003459 | 0.84 | MAPT (0.65) | ALDH1A1CSNK1DMAPTMAOBHSD17B1 | |
| SCHEMBL7158014 | 0.84 | MAPT (0.64) | ALDH1A1CSNK1DMAPTMAOBHSD17B1 | |
| SCHEMBL730623 | 0.76 | ALDH1A1 (0.65) | ALDH1A1MAOBHSD17B1HSD17B2CYP1A2 | |
| SCHEMBL26070209 | 0.76 | MAPT (0.47) | CSNK1DMAPTMAOBMAOATDP1 | |
| SCHEMBL20832544 | 0.75 | ALDH1A1 (0.67) | ALDH1A1MAPTMAOBMAOALMNA | |
| SCHEMBL20899481 | 0.75 | ALDH1A1 (0.63) | ALDH1A1CSNK1DMAPTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | ALDH1A1 1611/4885CSNK1D 684/4885MAPT 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.