Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726706 | 0.89 | RAB9A (0.68) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL218018 | 0.88 | MAPT (0.78) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| Hydrogen Sulfide SCHEMBL28326954 | 0.86 | MAPT (0.75) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| Phosphine SCHEMBL30201038 | 0.86 | MAPT (0.75) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| Ammonia Solution, Strong SCHEMBL29558993 | 0.86 | MAPT (0.75) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| Iodide SCHEMBL10484653 | 0.84 | MAPT (0.72) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL16986581 | 0.84 | ALDH1A1 (0.67) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL6296057 | 0.83 | BAZ1A (0.74) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL9948773 | 0.82 | MAPT (0.70) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL5528929 | 0.82 | MAPT (0.70) | MAPTL3MBTL1CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366018-A1 | OMEGA-AMINOALKYLAMIDES OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | Dompé S.P.A. (IT) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002068377-A1 | OMEGA-AMINOALKYLAMIDES OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | Dompé S.p.A. (IT) | 2002-09-06 | — | — | WO | disclosed |