Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11840328 | 0.72 | ALDH1A1 (0.45) | CYP3A4MEN1KMT2AHPGDTDP1 | |
| SCHEMBL5780751 | 0.71 | CA2 (0.45) | CYP3A4MEN1KMT2AHPGDTDP1 | |
| SCHEMBL9743229 | 0.71 | MAPKAPK2 (0.40) | CYP3A4MEN1KMT2AHPGDBACE1 | |
| SCHEMBL12378891 | 0.71 | BACE1 (0.39) | CYP3A4MEN1KMT2AHPGDBACE1 | |
| Phloroglucinol SCHEMBL27994526 | 0.70 | BACE1 (0.67) | CYP3A4MEN1KMT2AHPGDBACE1 | |
| Lithium SCHEMBL31440637 | 0.69 | BACE1 (0.37) | CYP3A4MEN1KMT2AHPGDBACE1 | |
| SCHEMBL7452126 | 0.67 | ACHE (0.39) | CYP3A4MEN1KMT2AHPGDFASN | |
| SCHEMBL23510833 | 0.67 | ALDH1A1 (0.39) | CYP3A4MEN1KMT2AHPGDBACE1 | |
| SCHEMBL19024853 | 0.67 | BACE1 (0.41) | CYP3A4MEN1KMT2AHPGDBACE1 | |
| SCHEMBL3019632 | 0.67 | BACE1 (0.50) | CYP3A4MEN1KMT2AHPGDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528655-B1 | Hydroxyphenyl diamido derivatives | PHARMACOR, INC. (CA) | 2003-03-04 | — | — | US | disclosed |
| US-5691341-A | ANTILEUKEMIA AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| US-5464833-A | Anticarcinogenic agents, antiretrovirus agents or autoimmune diseases | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0623598-A1 | APOPTOSIS REGULATOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |