Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19024853 | 0.94 | BACE1 (0.41) | BACE1CA12CA9CA2CA14 | |
| Phloroglucinol SCHEMBL27994526 | 0.79 | BACE1 (0.67) | BACE1CA12CA9CA2CA14 | |
| SCHEMBL356245 | 0.75 | — | — | |
| SCHEMBL3471002 | 0.73 | EGFR (0.31) | EGFR | |
| Phloroglucinol SCHEMBL11060846 | 0.73 | BACE1 (0.57) | BACE1CA12CA9CA2CA14 | |
| SCHEMBL674063 | 0.73 | BACE1 (0.57) | BACE1CA12CA9CA2CA14 | |
| Phloroglucinol SCHEMBL28193058 | 0.73 | BACE1 (0.57) | BACE1CA12CA9CA2CA14 | |
| SCHEMBL132438 | 0.73 | KDM4E (0.42) | CA12CA9CA2CA14CA1 | |
| SCHEMBL910840 | 0.73 | — | — | |
| SCHEMBL7291255 | 0.72 | ALDH1A1 (0.42) | ACHELMNAALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997007129-A1 | SOLUTION SYNTHESIS OF PERIPHERAL ACTING ANALGESIC OPIOID TETRAPEPTIDES | BIOCHEM PHARMA INC. (CA) | 1997-02-27 | — | — | WO | claimed |
| CN-109196004-B | Engineered scaffold for vascularized tissue repair | 加利福尼亚大学董事会 | 2022-03-18 | — | — | CN | disclosed |
| US-10918683-B2 | Methods to reduce fat accumulation and oxidative damage in liver using green mango extracts and compounds obtained therefrom | TCI CO., LTD. (TW) | 2021-02-16 | — | — | US | disclosed |
| CN-110680825-A | Mango young fruit extract and application of compound thereof in preparing pharmaceutical composition for reducing fat accumulation or oxidative damage of liver cells | 大江生医股份有限公司 | 2020-01-14 | — | — | CN | disclosed |
| CN-107236106-B | Aromatic hydroxyl-terminated chain extender containing acylhydrazone bond, self-repairing polyurethane and preparation method of chain extender | 青岛科技大学 | 2020-01-07 | — | — | CN | disclosed |
| CN-109761944-A | A kind of chrysin amide derivatives and preparation method thereof and medical usage | 武汉翼博济生生物科技有限公司 | 2019-05-17 | — | — | CN | disclosed |
| CN-108459000-A | Time-resolved fluorescence test strip for detecting fluopyram and application thereof | 北方工业大学 | 2018-08-28 | — | — | CN | disclosed |
| CN-108367179-A | TOPICAL DELIVERY SYSTEM FOR ACTIVE INGREDIENTS | 莱雅公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-107329367-A | Photosensitive resin composition, method for producing cured relief pattern, semiconductor device, and display device | 旭化成株式会社 | 2017-11-07 | — | — | CN | disclosed |
| CN-107072898-A | Composition in the form of a nanoemulsion or microemulsion or with a layered structure | 莱雅公司 | 2017-08-18 | — | — | CN | disclosed |
| US-5691341-A | ANTILEUKEMIA AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5681604-A | PLANT EXTRACTS; GREEN TEA, TANNIC ACID, EPICATECHIN GALLATE, GALLIC ACID CARBOHYDRATE REACTION PRODUCTS | DELAWARE, UNIVERSITY OF | 1997-10-28 | — | — | US | disclosed |
| WO-1997007129-A1 | SOLUTION SYNTHESIS OF PERIPHERAL ACTING ANALGESIC OPIOID TETRAPEPTIDES | BIOCHEM PHARMA INC. (CA) | 1997-02-27 | — | — | WO | disclosed |
| US-5464833-A | Anticarcinogenic agents, antiretrovirus agents or autoimmune diseases | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| US-5459142-A | Autoimmune disease, atherosclerosis, antiischemic agents and nephritis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| EP-0511879-B1 | Pyrazine derivatives | OTSUKA PHARMA CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| EP-0623598-A1 | APOPTOSIS REGULATOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10918683-B2 | Methods to reduce fat accumulation and oxidative damage in liver using green mango extracts and compounds obtained therefrom | LIPC, GOT2, PNLIP | BACE1 1501/4885CA12 4167/4885CA9 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.