Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7158828 | 0.82 | MAPK1 (0.36) | GRNSORT1MAPK1KEAP1CTSK | |
| SCHEMBL17291698 | 0.81 | CTSK (0.36) | GRNSORT1MAPK1CYP2C9CTSK | |
| SCHEMBL19057894 | 0.78 | MEN1 (0.34) | GRNSORT1CTSKMEN1GAA | |
| SCHEMBL9791459 | 0.77 | TGFBR1 (0.37) | MEN1KMT2ATGFBR1 | |
| SCHEMBL771831 | 0.77 | TGFBR1 (0.37) | MEN1KMT2ATGFBR1 | |
| SCHEMBL5048325 | 0.77 | GRN (0.50) | GRNSORT1MAPK1KEAP1PYGL | |
| SCHEMBL1693987 | 0.77 | GRN (0.50) | GRNSORT1MAPK1KEAP1PYGL | |
| SCHEMBL1693084 | 0.77 | GRN (0.50) | GRNSORT1MAPK1KEAP1PYGL | |
| SCHEMBL978015 | 0.76 | GRN (0.49) | GRNSORT1MAPK1KEAP1PYGL | |
| SCHEMBL18515857 | 0.76 | GRN (0.56) | GRNSORT1MAPK1KEAP1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534627-B1 | Using FMOC (9-fluorenylmethyloxycarbonyl) and tert-butyl containing compounds as protecting group; efficiency and storage stability | RESEARCH CORPORATION TECNOLOGIES, INC. | 2003-03-18 | — | — | US | disclosed |
| US-6040422-A | REACTING A FLUOROFORMAMIDINIUM SALT WITH AN N-AMINO PROTECTED, OPTIONALLY SIDE CHAIN PROTECTED AMINO ACID; THEN REACTING PRODUCT WITH A CARBOXY PROTECTED AMINO ACID; FOR COMPOUNDS WITH LONG TERM STORAGE STABILITY | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-03-21 | — | — | US | disclosed |
| US-5750767-A | REACTING PROTECTED AMINO ACID WITH FLUOROFORMAMIDINIUM SALT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5712418-A | FLUOROFORMAMIDINIUM SALTS AS FLUORINATION AGENTS TO FORM PEPTIDES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-01-27 | — | — | US | disclosed |
| WO-1996004297-A1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-02-15 | — | — | WO | disclosed |
| EP-0496836-B1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | RES CORP TECHNOLOGIES INC (US) | 1995-06-14 | — | — | EP | disclosed |
| US-5360928-A | Synthesis and use of amino acid fluorides as peptide coupling reagents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-11-01 | — | — | US | disclosed |
| EP-0496836-A4 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0496836-A1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS. | RES CORP TECHNOLOGIES INC (US) | 1992-08-05 | — | — | EP | disclosed |
| WO-1991005564-A1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |