Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4706854 | 0.82 | CTSK (0.40) | CTSKPOLBNPSR1TDP1ITGA4 | |
| SCHEMBL7158828 | 0.81 | MAPK1 (0.36) | CTSKGRNSORT1MAPK1 | |
| Fluoride SCHEMBL7158831 | 0.81 | GRN (0.46) | CTSKGRNSORT1MAPK1CYP2C9 | |
| SCHEMBL29022125 | 0.81 | CTSK (0.34) | CTSKPOLBNPSR1TDP1ITGA4 | |
| SCHEMBL13925605 | 0.79 | CYP2D6 (0.40) | CTSKPOLBNPSR1TDP1ITGA4 | |
| SCHEMBL13925615 | 0.79 | NPSR1 (0.45) | CTSKMAPK1POLBNPSR1TDP1 | |
| SCHEMBL13993198 | 0.79 | GRN (0.43) | CTSKGRNSORT1MAPK1POLB | |
| SCHEMBL22262968 | 0.79 | MAPK1 (0.38) | CTSKGRNSORT1MAPK1POLB | |
| SCHEMBL23051973 | 0.77 | GRN (0.39) | CTSKGRNSORT1MAPK1POLB | |
| SCHEMBL25453637 | 0.77 | MAPK1 (0.41) | CTSKGRNSORT1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344404-A1 | PDK4 INHIBITOR AND USE THEREOF | THE KITASATO INSTITUTE (JP) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344404-A1 | PDK4 INHIBITOR AND USE THEREOF | PDK4, PDK3, PDK2 | CTSK 816/4885GRN 3532/4885SORT1 4879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.