Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154961 | 0.88 | PPARG (0.49) | PPARGPPARAENPP3ENPP1FFAR1 | |
| SCHEMBL7227753 | 0.77 | ADCY1 (0.47) | PPARGPPARAENPP3ENPP1FFAR1 | |
| SCHEMBL5225166 | 0.75 | DAGLA (0.46) | PPARGPPARAFFAR1 | |
| SCHEMBL7210652 | 0.72 | ALDH1A1 (0.47) | PPARGPPARAENPP3ENPP1RAB9A | |
| SCHEMBL14701593 | 0.71 | ALDH1A1 (0.46) | ENPP3ENPP1RAB9APOLBNPC1 | |
| SCHEMBL7159209 | 0.71 | FFAR1 (0.56) | PPARGPPARAENPP3ENPP1FFAR1 | |
| SCHEMBL23558942 | 0.69 | ALDH1A1 (0.44) | ENPP3ENPP1RAB9APOLBNPC1 | |
| SCHEMBL7158026 | 0.69 | ALDH1A1 (0.47) | PPARGPPARAENPP3ENPP1RAB9A | |
| SCHEMBL30765878 | 0.69 | ALDH1A1 (0.47) | ENPP3ENPP1RAB9APOLBNPC1 | |
| Hydrochloric Acid SCHEMBL30765949 | 0.68 | ALDH1A1 (0.46) | ENPP3ENPP1RAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541497-B1 | Amino acid derivatives of benzoxazin-2-ylaminoalkoxyphenylalkyl compounds | ELI LILLY AND COMPANY | 2003-04-01 | — | — | US | disclosed |
| US-6353027-B1 | ENANTIOMORPHIC AMINE DERIVATIVES FOR TREATMENT OF DIABETES | ELI LILLY AND COMPANY | 2002-03-05 | — | — | US | disclosed |
| US-6194446-B1 | NON-INSULIN DEPENDENT DIABETES | ELI LILLY AND COMPANY | 2001-02-27 | — | — | US | disclosed |