Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154961 | 0.80 | PPARG (0.49) | ADCY1PPARGPPARAALDH1A1RAB9A | |
| SCHEMBL7159207 | 0.77 | PPARG (0.47) | ADCY1PPARGPPARAALDH1A1MAPT | |
| SCHEMBL7221412 | 0.76 | ENPP3 (0.62) | ALDH1A1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL29523345 | 0.74 | LTB4R (0.57) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29035407 | 0.74 | LTB4R (0.57) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29523814 | 0.74 | LTB4R (0.57) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3647221 | 0.74 | MAPT (0.57) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7227759 | 0.74 | MAPT (0.56) | PPARGPPARAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7217142 | 0.73 | ENPP3 (0.48) | ALDH1A1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL1123238 | 0.73 | MAPT (0.55) | PPARGPPARAMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617342-B1 | Treating hyperglycemia associated with non- insulin dependant diabetes and for treating hyperlipidemia. | ELI LILLY AND COMPANY | 2003-09-09 | — | — | US | disclosed |