Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.83 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.83 |
| ▸ | F2 | P00734 | 6/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lamifiban SCHEMBL871446 | 0.91 | ITGB3 (1.00) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| Lamifiban SCHEMBL4683 | 0.91 | ITGB3 (1.00) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7285135 | 0.84 | ITGB3 (0.82) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7282972 | 0.83 | ITGB3 (0.86) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL8382276 | 0.81 | ITGB3 (0.82) | ITGB3ITGA2B | |
| SCHEMBL7284586 | 0.81 | ITGB3 (0.82) | ITGB3ITGA2B | |
| SCHEMBL7292028 | 0.81 | ITGB3 (0.82) | ITGB3ITGA2BF2PLG | |
| SCHEMBL7284349 | 0.81 | ITGB3 (0.82) | ITGB3ITGA2BF2PLG | |
| SCHEMBL13933091 | 0.80 | ITGB3 (0.83) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL8383672 | 0.80 | ITGB3 (0.80) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6538112-B2 | Diagnosing a patient at risk to thrombocytopenia induced by administration of a GP IIb/llla receptor antagonist | MERCK & CO., INC. | 2003-03-25 | — | — | US | disclosed |
| US-20020009753-A1 | Anticoagulant test | BEDNAR BOHUMIL (US) | 2002-01-24 | — | — | US | disclosed |
| US-6210904-B1 | DIAGNOSING FOR RISK OF THROMOCYTOPENIA BY DETECTING ABSENCE OF ASSOCIATION OF MONOCLONAL ANTIBODY WITH GLYCOPROTEIN IIB/IIA RECEPTOR:GLYCOPROTEIN IIB/IIA RECEPTOR ANTAGONIST COMPLEX | MERCK & CO., INC. | 2001-04-03 | — | — | US | disclosed |