Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455401 | 0.88 | ALDH1A1 (0.72) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL4915910 | 0.87 | RAB9A (0.66) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL7163069 | 0.84 | GRIN2D (0.62) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL7169916 | 0.82 | GRIN2B (0.61) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL28296511 | 0.78 | RAB9A (0.73) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL7199038 | 0.78 | ALDH1A1 (0.51) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL28294795 | 0.77 | HRH4 (0.74) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL4916710 | 0.76 | HRH4 (0.64) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL7158838 | 0.74 | GRIN2D (0.62) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL7159377 | 0.73 | GRIN2B (0.64) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328514-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002034718-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2002-05-02 | — | — | WO | disclosed |