Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159351 | 0.78 | RAB9A (0.56) | ALDH1A1POLBMAPTHPGDL3MBTL1 | |
| SCHEMBL28296511 | 0.77 | RAB9A (0.73) | ALDH1A1POLBMAPTHPGDL3MBTL1 | |
| SCHEMBL28294795 | 0.76 | HRH4 (0.74) | ALDH1A1POLBMAPTHPGDL3MBTL1 | |
| SCHEMBL7163069 | 0.76 | GRIN2D (0.62) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4146496 | 0.75 | HSP90AA1 (0.56) | ALDH1A1POLBCA12CA1CA2 | |
| SCHEMBL7169916 | 0.74 | GRIN2B (0.61) | ALDH1A1POLBMAPTHPGDL3MBTL1 | |
| SCHEMBL27346073 | 0.72 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL3644984 | 0.69 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL3644986 | 0.69 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL6047288 | 0.69 | ALDH1A1 (0.56) | ALDH1A1POLBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328514-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002034718-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2002-05-02 | — | — | WO | disclosed |