Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27584983 | 0.92 | PTGS2 (0.67) | PTGS2PTGS1L3MBTL1MEN1KMT2A | |
| Sulfamide SCHEMBL7145902 | 0.91 | PTGS2 (0.81) | PTGS2PTGS1PDPK1ABCB11ALDH1A1 | |
| Sulfamide SCHEMBL7143375 | 0.88 | PTGS2 (0.76) | PTGS2PTGS1PDPK1ABCB11ALDH1A1 | |
| SCHEMBL6339240 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1PDPK1ABCB11ALDH1A1 | |
| SCHEMBL212658 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1PDPK1ABCB11ALDH1A1 | |
| SCHEMBL6339195 | 0.86 | PTGS2 (0.90) | PTGS2PTGS1PDPK1ABCB11ALDH1A1 | |
| Sulfamide SCHEMBL7141639 | 0.84 | PTGS2 (0.78) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL6456607 | 0.82 | PTGS2 (0.70) | PTGS2PTGS1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL7773921 | 0.82 | PTGS2 (0.65) | PTGS2PTGS1PDPK1ABCB11ALDH1A1 | |
| SCHEMBL8292457 | 0.82 | PTGS2 (0.71) | PTGS2PTGS1PDPK1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854723-B1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR USE IN VETERINARY THERAPIES AS ANTIINFLAMMATORY AGENTS | SEARLE & CO (US) | 2003-04-23 | — | — | EP | claimed |