Sugi Predict

Sugi Predict / Compounds / Sulfamide

Sulfamide

Sulfamide

SCHEMBL7145902

FC(F)c1cc(-c2ccccc2)n(-c2ccccc2)n1.NS(N)(=O)=O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 17/20 0.81
▸ PTGS1 P23219 10/20 0.81
▸ ABCB11 O95342 1/20 0.51
▸ ALDH1A1 P00352 1/20 0.51
▸ PDPK1 O15530 1/20 0.50
▸ RPA1 P27694 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6456607 0.91 PTGS2 (0.70) PTGS2PTGS1ALDH1A1RPA1
Sulfamide SCHEMBL7159984 0.91 PTGS2 (0.76) PTGS2PTGS1ABCB11ALDH1A1PDPK1
Sulfamide SCHEMBL7143375 0.91 PTGS2 (0.76) PTGS2PTGS1ABCB11ALDH1A1PDPK1
SCHEMBL6339195 0.89 PTGS2 (0.90) PTGS2PTGS1ABCB11ALDH1A1PDPK1
SCHEMBL215341 0.89 PTGS2 (1.00) PTGS2PTGS1ABCB11ALDH1A1PDPK1
Sulfamide SCHEMBL7141639 0.88 PTGS2 (0.78) PTGS2PTGS1ABCB11ALDH1A1RPA1
SCHEMBL3249718 0.87 PTGS2 (0.95) PTGS2PTGS1ABCB11ALDH1A1PDPK1
SCHEMBL6729799 0.84 PTGS2 (0.67) PTGS2PTGS1ABCB11ALDH1A1PDPK1
SCHEMBL9002626 0.84 PTGS2 (0.77) PTGS2PTGS1
SCHEMBL8765170 0.84 PTGS2 (0.70) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0854723-B1 SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR USE IN VETERINARY THERAPIES AS ANTIINFLAMMATORY AGENTS SEARLE & CO (US) 2003-04-23 — — EP claimed