Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | KDM5C | P41229 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18584520 | 0.80 | FEN1 (0.51) | KDM5AKDM5CKDM5BALDH1A1KDM4E | |
| SCHEMBL356250 | 0.79 | KDM5A (0.49) | KDM5AKDM5CKDM5BALDH1A1KDM4E | |
| SCHEMBL7079071 | 0.78 | KDM5A (0.48) | KDM5AKDM5CKDM5BALDH1A1KDM4E | |
| SCHEMBL13279916 | 0.76 | KDM5A (0.46) | KDM5AKDM5CKDM5BALDH1A1KDM4E | |
| SCHEMBL2126317 | 0.75 | KDM5A (0.57) | KDM5AKDM5CKDM5BALDH1A1KDM4E | |
| SCHEMBL359150 | 0.75 | KDM5A (0.57) | KDM5AKDM5CKDM5BALDH1A1KDM4E | |
| SCHEMBL7080667 | 0.75 | KDM5A (0.45) | KDM5AKDM5CKDM5BALDH1A1KDM4E | |
| SCHEMBL7078810 | 0.72 | KDM5A (0.43) | KDM5AKDM5CKDM5BXDHALDH1A1 | |
| SCHEMBL2056351 | 0.72 | PDE9A (0.54) | KDM5AKDM5CKDM5BALDH1A1KDM4E | |
| SCHEMBL6434650 | 0.72 | XDH (0.48) | XDHALDH1A1KDM4EMEN1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059356-A2 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |