SCHEMBL7160448

SCHEMBL7160448

NC(CO)CCS(=O)(=O)O

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
SLC6A6 P31641 1/20 0.42
CYP2C19 P33261 1/20 0.42
BLM P54132 1/20 0.42
S1PR2 O95136 1/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
APP P05067 1/20 0.39
PTGS1 P23219 1/20 0.36
PDE4A P27815 1/20 0.36
ENPEP Q07075 5/20 0.35
TP53 P04637 2/20 0.31
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28606531 0.86 APP (0.46) LMNASLC6A6CYP2C19BLMS1PR2
SCHEMBL4744742 0.83 S1PR2 (0.44) LMNASLC6A6CYP2C19BLMS1PR2
SCHEMBL7639998 0.80 LMNA (0.42) LMNASLC6A6CYP2C19BLMS1PR2
SCHEMBL999249 0.80 LMNA (0.48) LMNASLC6A6CYP2C19BLMS1PR2
SCHEMBL7621164 0.79 S1PR2 (0.45) LMNASLC6A6CYP2C19BLMS1PR2
SCHEMBL7436774 0.78 PMP22 (0.38) S1PR2S1PR1S1PR3ENPEPTP53
SCHEMBL29180212 0.78 PMP22 (0.38) S1PR2S1PR1S1PR3ENPEPTP53
Ec33 SCHEMBL2310959 0.78 ENPEP (0.59) LMNASLC6A6CYP2C19BLMS1PR2
SCHEMBL820427 0.78 LMNA (0.52) LMNASLC6A6CYP2C19BLMS1PR2
Ec33 SCHEMBL1291100 0.78 ENPEP (0.59) LMNASLC6A6CYP2C19BLMS1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112255395-A Method for eliminating chyle interference in lipemic sample, immunoturbidimetry kit and application 中生北控生物科技股份有限公司 2021-01-22 CN claimed
CN-112255395-B Method for eliminating chyle interference in lipemic sample, immunoturbidimetry kit and application 中生北控生物科技股份有限公司 2021-06-18 CN disclosed
CN-112255395-A Method for eliminating chyle interference in lipemic sample, immunoturbidimetry kit and application 中生北控生物科技股份有限公司 2021-01-22 CN disclosed
EP-1317539-A2 DIRECTED EVOLUTION METHOD MEDICAL RESEARCH COUNCIL (GB) 2003-06-11 EP disclosed
WO-2002022869-A2 DIRECTED EVOLUTION METHOD MEDICAL RESEARCH COUNCIL (GB) 2002-03-21 WO disclosed