Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27651670 | 0.94 | S1PR2 (0.44) | S1PR2S1PR1S1PR3APPLMNA | |
| SCHEMBL27651658 | 0.92 | S1PR2 (0.46) | S1PR2S1PR1S1PR3APPLMNA | |
| SCHEMBL4744742 | 0.86 | S1PR2 (0.44) | S1PR2S1PR1S1PR3APPLMNA | |
| SCHEMBL28586828 | 0.81 | APP (0.54) | S1PR2S1PR1S1PR3APPLMNA | |
| SCHEMBL353077 | 0.81 | S1PR2 (0.59) | S1PR2S1PR1S1PR3APPENPEP | |
| SCHEMBL2168312 | 0.80 | ENPEP (0.40) | S1PR2S1PR1S1PR3APPENPEP | |
| SCHEMBL7160448 | 0.79 | LMNA (0.42) | S1PR2S1PR1S1PR3APPLMNA | |
| Sulfuric Acid SCHEMBL1833455 | 0.78 | APP (0.39) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL27810744 | 0.78 | LTA4H (0.33) | APPENPEPTP53 | |
| Sulfuric Acid SCHEMBL1833456 | 0.78 | APP (0.39) | APPLMNASLC6A6CYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237547-A2 | COMPOUNDS FOR INHIBITING DISEASES AND PREPARING CELLS FOR TRANSPLANTATION | ISIS INNOVATION LIMITED (GB) | 2002-09-11 | — | — | EP | claimed |
| WO-2001003680-A2 | COMPOUNDS FOR INHIBITING DISEASES AND PREPARING CELLS FOR TRANSPLANTATION | ISIS INNOVATION LIMITED (GB) | 2001-01-18 | — | — | WO | claimed |
| US-9763900-B2 | Chemical chaperonins as novel molecular modulators of beta protein aggregation present in conformational diseases | CENTRO DE NEUROCIENCIAS DE CUBA (CU) | 2017-09-19 | — | — | US | disclosed |
| US-20160106691-A1 | CHEMICAL CHAPERONINS AS NOVEL MOLECULAR MODULATORS OF BETA PROTEIN AGGREGATION PRESENT IN CONFORMATIONAL DISEASES | CENTRO DE NEUROCIENCIAS DE CUBA (NEURONIC) (CU) | 2016-04-21 | — | — | US | disclosed |
| EP-1237547-A2 | COMPOUNDS FOR INHIBITING DISEASES AND PREPARING CELLS FOR TRANSPLANTATION | ISIS INNOVATION LIMITED (GB) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001003680-A2 | COMPOUNDS FOR INHIBITING DISEASES AND PREPARING CELLS FOR TRANSPLANTATION | ISIS INNOVATION LIMITED (GB) | 2001-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160106691-A1 | CHEMICAL CHAPERONINS AS NOVEL MOLECULAR MODULATORS OF BETA PROTEIN AGGREGATION PRESENT IN CONFORMATIONAL DISEASES | HSPA2, HSPB1, HSP90AB2P | S1PR2 4479/4885S1PR1 4814/4885S1PR3 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.