Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CDH1 | P12830 | 1/20 | 0.56 |
| ▸ | APC | P25054 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.56 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269138 | 0.81 | ALDH1A1 (0.66) | ALDH1A1GAAHPGDRAB9AKDM4E | |
| SCHEMBL4340852 | 0.79 | ERN1 (0.61) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL106249 | 0.79 | CASP6 (0.72) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2636747 | 0.79 | CASP6 (0.72) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL15666198 | 0.78 | ALDH1A1 (0.74) | ALDH1A1GAAHPGDRAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL1259208 | 0.77 | HPGD (0.60) | ALDH1A1GAAHPGDRAB9AKDM4E | |
| SCHEMBL1898142 | 0.77 | CASP6 (0.70) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL9469176 | 0.77 | CASP6 (0.70) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL1258992 | 0.76 | ALDH1A1 (0.76) | ALDH1A1GAAHPGDRAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL10607831 | 0.76 | CASP6 (0.68) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608171-B1 | Containing solubilizing pendant groups or flexible units; processability | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2003-08-19 | — | — | US | disclosed |
| US-6541633-B1 | 2,3-bis(3-amino-4-hydroxy or 4-mercapto or 4-NH2.HCLphenyl)quinoxaline-6- carboxylic acid dihydrochloride monomer, which self-polymerizes to form hyperbranched polybenzoxazoles, polybenzothizoles etc. | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2003-04-01 | — | — | US | disclosed |