SCHEMBL106249

SCHEMBL106249

O=C(O)c1ccc(O)c([N+](=O)[O-])c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 1/20 0.72
TSHR P16473 3/20 0.66
LMNA P02545 1/20 0.66
HCAR3 P49019 8/20 0.60
MAPK1 P28482 2/20 0.58
ALDH1A1 P00352 1/20 0.58
TP53 P04637 1/20 0.58
HPGD P15428 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
GPR35 Q9HC97 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.56
ALOX15 P16050 1/20 0.56
HSD17B10 Q99714 1/20 0.56
APEX1 P27695 1/20 0.55
KDM4E B2RXH2 1/20 0.55
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
POLB P06746 1/20 0.55
GAA P10253 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2636747 1.00 CASP6 (0.72) CASP6TSHRLMNAHCAR3MAPK1
SCHEMBL1898142 0.98 CASP6 (0.70) CASP6TSHRLMNAHCAR3MAPK1
SCHEMBL9469176 0.98 CASP6 (0.70) CASP6TSHRLMNAHCAR3MAPK1
Hydrochloric Acid SCHEMBL10607831 0.96 CASP6 (0.68) CASP6TSHRLMNAHCAR3MAPK1
Benzoic Acid SCHEMBL28359564 0.93 CASP6 (0.64) CASP6TSHRLMNAHCAR3MAPK1
SCHEMBL7103159 0.86 VCAM1 (0.65) CASP6TSHRLMNAMAPK1ALDH1A1
SCHEMBL2156599 0.86 MAPK1 (0.60) CASP6TSHRLMNAMAPK1ALDH1A1
SCHEMBL4340852 0.86 ERN1 (0.61) CASP6TSHRLMNAMAPK1ALDH1A1
SCHEMBL9660912 0.85 GPR35 (0.55) CASP6TSHRLMNAHCAR3MAPK1
SCHEMBL459609 0.85 CASP6 (0.72) CASP6TSHRLMNAHCAR3TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 834 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
WO-2025075611-A1 ULTRASONIC INDICATOR BASED ON EMULSION FORMATION JP LABORATORIES, INC. (US) 2025-04-10 WO claimed
CN-119176926-A Macroporous polyurethane resin for specifically adsorbing scutellarin and preparation method and application thereof 楚雄云植药业有限公司 2024-12-24 CN claimed
CN-116174053-A Catalyst composition for octene hydroformylation reaction and application method thereof 万华化学集团股份有限公司 2023-05-30 CN claimed
CN-110183348-B N- (3-nitro-4-alkoxy benzoyl) amino acid compound, preparation method and application thereof 中国医科大学 2022-06-03 CN claimed
CN-109821575-B Terbium-based metal organic framework material Tb-MOF, preparation method thereof and methylene blue dye photocatalytic degradation method 河海大学 2021-07-30 CN claimed
CN-109821574-B Europium-based metal organic framework material Eu-MOF, preparation method thereof and Congo red dye photocatalytic degradation method 河海大学 2021-07-30 CN claimed
CN-109821576-B Dysprosium-based metal organic framework material Dy-MOF, preparation method thereof and methylene blue dye photocatalytic degradation method 河海大学 2021-07-27 CN claimed
US-10626141-B2 Method for specific cleavage of C alpha-C bond and side chain of protein and peptide, and method for determining amino acid sequence SHIMADZU CORPORATION (JP) 2020-04-21 US claimed
EP-0374760-A1 Dioxane addition compounds of aromatic meta- or para-hydroxy-carboxylic acids, and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP claimed
EP-0206635-B1 PREPARATION OF 3-AMINO-4-HYDROXYBENZOIC ACIDS THE DOW CHEMICAL COMPANY (US) 1989-11-15 EP claimed
US-4835306-A Preparation of 3-amino-4-hydroxybenzoic acids THE DOW CHEMICAL COMPANY (US) 1989-05-30 US claimed
US-4812396-A REFRACTIVE PARTICLES WITH LIGAND COATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-03-14 US claimed
US-4812395-A REFRACTIVE PARTICLES WITH LIGAND COATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-03-14 US claimed
WO-1988009398-A1 ELECTROCHEMICAL SYNTHESIS OF SUBSTITUTED AMINES IN BASIC MEDIA THE DOW CHEMICAL COMPANY (US) 1988-12-01 WO claimed
EP-0291865-A2 Electrochemical synthesis of substituted aromatic amines in basic media THE DOW CHEMICAL COMPANY (US) 1988-11-23 EP claimed
US-4764263-A Electrochemical synthesis of substituted aromatic amines in basic media THE DOW CHEMICAL COMPANY (US) 1988-08-16 US claimed
EP-0206635-A1 Preparation of 3-amino-4-hydroxybenzoic acids THE DOW CHEMICAL COMPANY (US) 1986-12-30 EP claimed
EP-0181762-A2 Method for detecting enzymatic activity using particle agglutination E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-05-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10626141-B2 Method for specific cleavage of C alpha-C bond and side chain of protein and peptide, and method for determining amino acid sequence CPN1, CYBA, CRYAB CASP6 733/4885TSHR 4102/4885LMNA 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.