Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.35 |
| ▸ | RAB9A | P51151 | 8/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163093 | 0.87 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7164438 | 0.82 | NPSR1 (0.39) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6319700 | 0.75 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2FFAR4PTGER3 | |
| SCHEMBL7592864 | 0.70 | NQO2 (0.38) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7168221 | 0.69 | FFAR4 (0.33) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL17414697 | 0.67 | MAP3K14 (0.47) | NPC1RAB9ASMN1; SMN2FFAR4PTGER3 | |
| SCHEMBL29613083 | 0.66 | POLB (0.42) | NPC1RAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL9445127 | 0.64 | CYP2A6 (0.38) | NPC1RAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL1203845 | 0.63 | TSHR (0.46) | ALDH1A1 | |
| SCHEMBL1899075 | 0.63 | PTK2B (0.42) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095946-B1 | Optically active diphosphine compound, production intermediates therefor, transition metal complex containing the compound as ligand and asymmetric hydrogenation catalyst containing the complex | TAKASAGO PERFUMERY CO LTD (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6333291-B1 | USEFUL AS A LIGAND OF CATALYSTS FOR ASYMMETRIC SYNTHESIS REACTIONS SUCH AS ASYMMETRIC HYDROGENATION REACTION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-1095946-A1 | Optically active diphosphine compound, production intermediates therefor, transition metal complex containing the compound as ligand and asymmetric hydrogenation catalyst containing the complex | Takasago International Corporation (JP) | 2001-05-02 | — | — | EP | disclosed |