Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319700 | 0.88 | NPC1 (0.35) | ALDH1A1TSHRNPC1MAPTRAB9A | |
| SCHEMBL7594183 | 0.87 | HSP90AA1 (0.37) | NQO2CYP19A1ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL7596886 | 0.86 | NQO2 (0.36) | NQO2CYP19A1ALDH1A1TSHRNPC1 | |
| SCHEMBL7594464 | 0.82 | NQO2 (0.36) | NQO2CYP19A1TSHRNPC1MAPT | |
| SCHEMBL7642818 | 0.82 | ALDH1A1 (0.34) | NQO2CYP19A1ALDH1A1HSP90AA1CYP3A4 | |
| SCHEMBL7592861 | 0.80 | NPC1 (0.37) | ALDH1A1CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL7599038 | 0.78 | NPC1 (0.37) | ALDH1A1HSP90AA1HSP90AB1TSHRNPC1 | |
| SCHEMBL7594461 | 0.77 | RAB9A (0.40) | NQO2CYP19A1ALDH1A1NPC1MAPT | |
| SCHEMBL7598402 | 0.77 | ALDH1A1 (0.35) | NQO2CYP19A1ALDH1A1HSP90AA1CYP3A4 | |
| SCHEMBL7645402 | 0.77 | CYP19A1 (0.34) | NQO2CYP19A1HSP90AA1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850945-B1 | Chiral diphosphine compound, intermediate for preparing the same, transition metal complex having the same diphosphine compound as ligand and asymmetric hydrogenation catalyst | TAKASAGO PERFUMERY CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6472539-B1 | BASIFICATION OF MONOMER WITH SUCH AS BUTYLLITHIUM THEN DIMERIZATION IN NONPOLAR SOLVENT CONTAINING SUSPENDED OXIDATIVE METAL SALT SUCH AS FERRIC CHLORIDE; HIGH YIELD; CHEMICAL INTERMEDIATE TO ASYMMETRIC SYNTHESIS CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-10-29 | — | — | US | disclosed |
| US-5872273-A | LIGANDS FOR FORMING HYDROGENATION CATALYST COMPLEXES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0850945-A1 | Chiral diphosphine compound, intermediate for preparing the same, transition metal complex having the same diphosphine compound as ligand and asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 1998-07-01 | — | — | EP | disclosed |