Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 5/20 | 0.81 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.64 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.56 |
| ▸ | TTR | P02766 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.56 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.56 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Hydroxy-Diclofenac SCHEMBL2738864 | 0.90 | CAMK2A (1.00) | CAMK2APTGS2CXCL8TTRABCB11 | |
| 4'-Hydroxy-Diclofenac SCHEMBL155743 | 0.87 | CAMK2A (1.00) | CAMK2APTGS2CXCL8TTRABCB11 | |
| 4'-Hydroxy-Diclofenac SCHEMBL30350150 | 0.87 | CAMK2A (1.00) | CAMK2APTGS2CXCL8TTRABCB11 | |
| SCHEMBL20034267 | 0.85 | CAMK2A (0.64) | CAMK2APTGS2CXCL8TTRABCB11 | |
| SCHEMBL23691080 | 0.85 | TTR (0.62) | CAMK2APTGS2CXCL8TTRABCB11 | |
| SCHEMBL1030170 | 0.81 | PTGS2 (0.73) | CAMK2APTGS2CXCL8TTRABCB11 | |
| SCHEMBL10801656 | 0.79 | PTGS2 (0.61) | CAMK2APTGS2CXCL8TTRABCB11 | |
| SCHEMBL1032535 | 0.79 | PTGS2 (0.87) | CAMK2APTGS2CXCL8TTRABCB11 | |
| 4'-Hydroxy-Diclofenac SCHEMBL30753145 | 0.78 | CAMK2A (0.63) | CAMK2APTGS2CXCL8TTRABCB11 | |
| SCHEMBL2238912 | 0.77 | CAMK2A (0.59) | CAMK2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230642-A1 | HYDROXYLATION TECHNIQUES | HYPHA DISCOVERY LTD. (GB) | 2021-07-29 | — | — | US | disclosed |
| US-6552077-B2 | Kidney disorders | EXOCELL, INC. | 2003-04-22 | — | — | US | disclosed |
| US-6355680-B1 | BLOCKING REACTION OF GLUCOSE AND ALBUMIN | EXOCELL, INC. | 2002-03-12 | — | — | US | disclosed |
| US-20010034359-A1 | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies | EXOCELL, INC. | 2001-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034359-A1 | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies | ALB, AGER, TTR | CAMK2A 2988/4885PTGS2 2067/4885CXCL8 3032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.