Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 5/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17454712 | 0.90 | S1PR1 (0.34) | S1PR1S1PR3HDAC1HDAC6RXRA | |
| SCHEMBL16030206 | 0.90 | S1PR1 (0.41) | S1PR1S1PR3HDAC1HDAC6RXRA | |
| SCHEMBL17454661 | 0.88 | S1PR1 (0.40) | S1PR1S1PR3HDAC1HDAC6RXRA | |
| SCHEMBL716513 | 0.88 | RXRA (0.38) | S1PR1S1PR3HDAC1HDAC6RXRA | |
| SCHEMBL29037283 | 0.88 | RXRA (0.40) | S1PR1S1PR3HDAC1HDAC6RXRA | |
| SCHEMBL23803478 | 0.88 | RXRA (0.38) | S1PR1S1PR3HDAC1HDAC6RXRA | |
| SCHEMBL16029980 | 0.88 | HTR2C (0.40) | S1PR1S1PR3HDAC1HDAC6RXRA | |
| SCHEMBL16030050 | 0.87 | S1PR1 (0.40) | S1PR1S1PR3HDAC1HDAC6RXRA | |
| SCHEMBL21052642 | 0.87 | HDAC1 (0.41) | HDAC1HDAC6RXRAGRIN1GRIN2B | |
| SCHEMBL27859306 | 0.87 | ADORA3 (0.39) | S1PR1S1PR3HDAC1HDAC6RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551914-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-8551914-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-8551914-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-10-08 | — | — | US | disclosed |
| EP-2608667-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2013-07-03 | — | — | EP | disclosed |
| US-20120053216-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120053216-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120053216-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2012027521-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053216-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PLA2G4C | S1PR1 1690/4885S1PR3 815/4885HDAC1 2921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.