Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507891 | 0.82 | TPMT (0.44) | ALDH1A1ALDH3A1CA12CA1CA2 | |
| SCHEMBL5841267 | 0.80 | PKM (0.60) | ALDH1A1ALDH3A1PKMPOLBLMNA | |
| SCHEMBL1553581 | 0.72 | KMT2A (0.63) | ALDH1A1POLBLMNAMAPTSMN1; SMN2 | |
| SCHEMBL11687564 | 0.71 | LMNA (0.47) | ALDH1A1ALDH3A1LMNAMAPTGAA | |
| SCHEMBL18653823 | 0.71 | MAPT (0.62) | ALDH1A1ALDH3A1PKMPOLBLMNA | |
| SCHEMBL9461983 | 0.70 | GRIN2D (0.46) | ALDH1A1PKMPOLBLMNAMAPT | |
| SCHEMBL7813230 | 0.70 | CASP6 (0.57) | ALDH1A1ALDH3A1PKMPOLBLMNA | |
| SCHEMBL21772122 | 0.70 | KMT2A (0.47) | ALDH1A1PKMPOLBLMNAMAPT | |
| SCHEMBL21772089 | 0.70 | KMT2A (0.47) | PKMPOLBLMNAMAPTSMN1; SMN2 | |
| SCHEMBL27857853 | 0.70 | CA12 (0.41) | ALDH1A1POLBLMNAMAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1293213-A1 | PREVENTIVES/REMEDIES FOR POSTOPERATIVE STRESS | JAPAN TOBACCO INC. (JP) | 2003-03-19 | — | — | EP | disclosed |