Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.46 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653823 | 0.88 | MAPT (0.62) | PKMPOLBMAPTNPSR1ALDH3A1 | |
| SCHEMBL7591545 | 0.87 | MAPT (0.61) | PKMPOLBMAPTNPSR1ALDH3A1 | |
| SCHEMBL11629310 | 0.87 | ALDH3A1 (0.76) | PKMPOLBMAPTNPSR1ALDH3A1 | |
| SCHEMBL11686855 | 0.85 | CA1 (0.64) | PKMPOLBMAPTNPSR1ALDH3A1 | |
| SCHEMBL5786327 | 0.82 | KMT2A (0.78) | PKMPOLBMAPTNPSR1ALDH3A1 | |
| SCHEMBL22659052 | 0.81 | HCAR3 (0.54) | PKMPOLBMAPTALDH3A1ALDH1A1 | |
| SCHEMBL5951705 | 0.81 | KMT2A (0.53) | PKMPOLBMAPTALDH1A1KMT2A | |
| SCHEMBL10712446 | 0.80 | MAPT (0.64) | PKMPOLBMAPTNPSR1ALDH1A1 | |
| SCHEMBL7163402 | 0.80 | ALDH1A1 (0.47) | PKMPOLBMAPTNPSR1ALDH3A1 | |
| SCHEMBL2282371 | 0.80 | MAPT (0.68) | PKMPOLBMAPTNPSR1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10026553-B2 | Organic compound, crystal dielectric layer and capacitor | CAPACITOR SCIENCES INCORPORATED (US) | 2018-07-17 | — | — | US | disclosed |
| US-10026553-B2 | Organic compound, crystal dielectric layer and capacitor | CAPACITOR SCIENCES INCORPORATED (US) | 2018-07-17 | — | — | US | disclosed |
| WO-2017070249-A1 | ORGANIC COMPOUND, CRYSTAL DIELECTRIC LAYER AND CAPACITOR BACKGROUND | CAPACITOR SCIENCES INCORPORATED (US) | 2017-04-27 | — | — | WO | disclosed |
| US-20170117097-A1 | ORGANIC COMPOUND, CRYSTAL DIELECTRIC LAYER AND CAPACITOR | CAPACITOR SCIENCES INCORPORATED | 2017-04-27 | — | — | US | disclosed |
| US-20170117097-A1 | ORGANIC COMPOUND, CRYSTAL DIELECTRIC LAYER AND CAPACITOR | CAPACITOR SCIENCES INCORPORATED | 2017-04-27 | — | — | US | disclosed |
| US-7138530-B2 | Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-11-21 | — | — | US | disclosed |
| US-7109354-B2 | Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-09-19 | — | — | US | disclosed |
| EP-1549632-A4 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | DIMENSIONAL PHARM INC (US) | 2005-11-09 | — | — | EP | disclosed |
| US-20050234081-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | SUBASINGHE NALIN | 2005-10-20 | — | — | US | disclosed |
| EP-1549632-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-07-06 | — | — | EP | disclosed |
| US-20040009995-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2004-01-15 | — | — | US | disclosed |
| WO-2003099805-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-12-04 | — | — | WO | disclosed |
| US-5359132-A | Process for the preparation of sodium salts of aromatic sulphinic acids containing nitro groups | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-25 | — | — | US | disclosed |
| US-4567252-A | Water-insoluble naphthol monoazo dyestuff | CASSELLA AKTIENGESELLSCHAFT (DE) | 1986-01-28 | — | — | US | disclosed |
| EP-0096789-A1 | Water-insoluble monoazo dyestuffs, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1983-12-28 | — | — | EP | disclosed |
| US-4005199-A | Substituted benzenesulfonamides as anthelmintics | MERCK & CO., INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-3987199-A | PARASITICIDES | MERCK & CO., INC. (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234081-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | C5, C9, C1R | PKM 3263/4885POLB 4582/4885MAPT 3296/4885 |
| US-20170117097-A1 | ORGANIC COMPOUND, CRYSTAL DIELECTRIC LAYER AND CAPACITOR | PIEZO1, FOXO1, FOXM1 | PKM 1969/4885POLB 4101/4885MAPT 4560/4885 |
| US-20040009995-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | C5, C9, C1R | PKM 4070/4885POLB 4433/4885MAPT 2762/4885 |
| US-10026553-B2 | Organic compound, crystal dielectric layer and capacitor | PIEZO1, FOXO1, FOXM1 | PKM 1969/4885POLB 4101/4885MAPT 4560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.