Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174773 | 0.87 | VCAM1 (0.48) | VCAM1ALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL22116211 | 0.76 | ALDH1A1 (0.76) | VCAM1ALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL12087097 | 0.73 | VCAM1 (0.51) | VCAM1ALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL7169698 | 0.70 | VCAM1 (0.58) | VCAM1ALDH1A1HPGDGAAL3MBTL1 | |
| SCHEMBL5471880 | 0.70 | VCAM1 (1.00) | VCAM1ALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8542275 | 0.69 | ALDH1A1 (0.56) | VCAM1ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL11484396 | 0.67 | VCAM1 (0.65) | VCAM1ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL11640314 | 0.67 | VCAM1 (0.57) | VCAM1ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL9507891 | 0.67 | TPMT (0.44) | VCAM1ALDH1A1TDP1ALDH3A1 | |
| SCHEMBL7650160 | 0.66 | HTT (0.66) | VCAM1ALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1293213-A1 | PREVENTIVES/REMEDIES FOR POSTOPERATIVE STRESS | JAPAN TOBACCO INC. (JP) | 2003-03-19 | — | — | EP | disclosed |