Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305334 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL22116211 | 0.78 | ALDH1A1 (0.76) | ALDH1A1KMT2AVCAM1SMN1; SMN2MAPT | |
| SCHEMBL11744950 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AKDM4EVCAM1 | |
| SCHEMBL11744939 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AKDM4EVCAM1 | |
| SCHEMBL8542441 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AKDM4EVCAM1 | |
| SCHEMBL13717956 | 0.76 | VCAM1 (0.55) | ALDH1A1MEN1KMT2ATSHRVCAM1 | |
| SCHEMBL8540726 | 0.75 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL12087097 | 0.75 | VCAM1 (0.51) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL8414119 | 0.74 | GRIA2 (0.54) | TSHRVCAM1MAPTCYP3A4ALOX15 | |
| SCHEMBL124590 | 0.74 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584085-B1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5554606-A | THIENAMYCIN DERIVATIVES; PSEUDOMONAS | ZENECA LIMITED (GB) | 1996-09-10 | — | — | US | disclosed |
| EP-0584085-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992017479-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD. (GB) | 1992-10-15 | — | — | WO | disclosed |