Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164375 | 0.87 | VCAM1 (0.53) | VCAM1ALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL22116211 | 0.71 | ALDH1A1 (0.76) | VCAM1ALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL7169698 | 0.69 | VCAM1 (0.58) | VCAM1ALDH1A1HPGDALDH3A1KMT2A | |
| SCHEMBL12087097 | 0.69 | VCAM1 (0.51) | VCAM1ALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL9395762 | 0.67 | ALDH1A1 (0.47) | ALDH1A1POLBSMN1; SMN2LMNATDP1 | |
| SCHEMBL5471880 | 0.66 | VCAM1 (1.00) | VCAM1ALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9396448 | 0.65 | POLB (0.55) | ALDH1A1POLBHPGDSMN1; SMN2LMNA | |
| SCHEMBL9396479 | 0.65 | POLB (0.46) | ALDH1A1POLBHPGDSMN1; SMN2LMNA | |
| SCHEMBL8542275 | 0.65 | ALDH1A1 (0.56) | VCAM1ALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL11189207 | 0.64 | ALDH1A1 (0.55) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1293213-A1 | PREVENTIVES/REMEDIES FOR POSTOPERATIVE STRESS | JAPAN TOBACCO INC. (JP) | 2003-03-19 | — | — | EP | disclosed |