Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.33 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.32 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164282 | 0.79 | SRC (0.36) | SRCLMNAGGPS1PTPRCFDPS | |
| SCHEMBL5897154 | 0.78 | SRC (0.53) | SRCLMNAFDPSMEN1KMT2A | |
| SCHEMBL4679260 | 0.74 | FDPS (0.44) | LMNAFDPSKMT2AALDH1A1 | |
| Water SCHEMBL5177023 | 0.72 | FDPS (0.43) | LMNAFDPSKMT2AALDH1A1 | |
| SCHEMBL7158552 | 0.66 | GGPS1 (0.57) | ACHEGGPS1FDPS | |
| SCHEMBL9843250 | 0.65 | ACHE (0.52) | ACHEKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL30240545 | 0.65 | ACHE (0.52) | ACHEKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL130697 | 0.64 | INPPL1 (0.71) | SRCINPPL1INPP5AKDM4EMEN1 | |
| SCHEMBL12341192 | 0.64 | SRC (0.53) | ACHESRCLMNAINPPL1INPP5A | |
| SCHEMBL78769 | 0.64 | KMT2A (0.66) | ACHELMNAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548042-B2 | Such as tetraethyl-N-(m-trimethylsilylphenylethyl)amino-methylenebisphosphonate for palliative and curative treatment of bone disorders and breast cancer | ARSTAD ERIK (NO) | 2003-04-15 | — | — | US | disclosed |
| US-20020042539-A1 | Bis-phosphonate compounds | ARSTAD ERIK (NO) | 2002-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042539-A1 | Bis-phosphonate compounds | PHOSPHO1, PTMS, PTEN | ACHE 2316/4885SRC 531/4885LMNA 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.