Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5897154 | 0.80 | SRC (0.53) | SRCLMNAMEN1KMT2AFDPS | |
| SCHEMBL7165035 | 0.79 | ACHE (0.40) | SRCLMNAGGPS1PTPRCMEN1 | |
| SCHEMBL4679260 | 0.73 | FDPS (0.44) | LMNAKMT2AFDPSALDH1A1 | |
| Water SCHEMBL5177023 | 0.72 | FDPS (0.43) | LMNAKMT2AFDPSALDH1A1 | |
| SCHEMBL13301849 | 0.69 | LMNA (0.35) | SRCLMNAMEN1KMT2AHDAC1 | |
| SCHEMBL22619019 | 0.67 | MEN1 (0.47) | MEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL4189787 | 0.65 | KIF11 (0.41) | TP53BP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16753741 | 0.64 | PLG (0.41) | TP53BP1TBXA2R | |
| SCHEMBL16456183 | 0.64 | ELANE (0.51) | TP53BP1LMNAMEN1KMT2ATBXA2R | |
| SCHEMBL505384 | 0.63 | CYP2C19 (0.50) | SRCLMNAMEN1KMT2APTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548042-B2 | Such as tetraethyl-N-(m-trimethylsilylphenylethyl)amino-methylenebisphosphonate for palliative and curative treatment of bone disorders and breast cancer | ARSTAD ERIK (NO) | 2003-04-15 | — | — | US | disclosed |
| US-20020042539-A1 | Bis-phosphonate compounds | ARSTAD ERIK (NO) | 2002-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042539-A1 | Bis-phosphonate compounds | PHOSPHO1, PTMS, PTEN | SRC 531/4885TP53BP1 2114/4885LMNA 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.