Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 6/20 | 0.47 |
| ▸ | THRB | P10828 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.44 |
| ▸ | LSS | P48449 | 3/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166938 | 0.76 | THRA (0.51) | THRATHRBTP53TSHRLSS | |
| SCHEMBL7169877 | 0.76 | THRA (0.51) | THRATHRBTP53TSHRLSS | |
| SCHEMBL3365531 | 0.74 | LSS (0.61) | LSS | |
| SCHEMBL3365325 | 0.73 | LSS (0.78) | LSS | |
| SCHEMBL7201224 | 0.72 | SMN1; SMN2 (0.52) | THRATHRBTP53TSHRLSS | |
| SCHEMBL7178386 | 0.72 | THRA (0.47) | THRATHRBTP53TSHRMCHR1 | |
| SCHEMBL7166192 | 0.72 | THRA (0.49) | THRATHRBTP53TSHRLSS | |
| SCHEMBL17192957 | 0.72 | LSS (0.72) | THRATHRBTP53TSHRLSS | |
| SCHEMBL3365379 | 0.72 | LSS (0.64) | LSS | |
| SCHEMBL7173887 | 0.71 | LIPE (0.48) | THRATHRBTP53TSHRLSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303503-A2 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002006189-A2 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-24 | — | — | WO | disclosed |