SCHEMBL7357498

SCHEMBL7357498

CCCCOC(=O)N(C(C=O)CCCNC(=N)N)[N+](=O)[O-]

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.32
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8741285 0.83 ACHE (0.32) ACHEMGLL
SCHEMBL4961940 0.83 MEN1 (0.35)
SCHEMBL8740426 0.83 MEN1 (0.35)
SCHEMBL7165148 0.71 NPY4R (0.36)
SCHEMBL27494771 0.70 ACHE (0.37) ACHEMAPTRAB9ANPSR1
SCHEMBL4167389 0.70 DPP7 (0.46) ACHE
SCHEMBL578523 0.70 DPP7 (0.46) ACHE
SCHEMBL24131269 0.69 ALOX15 (0.36)
Hydrochloric Acid SCHEMBL10727145 0.69 DPP7 (0.45) ACHE
SCHEMBL7173030 0.69 DPP7 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684830-A4 INHIBITORS OF THROMBOSIS. CORVAS INT INC (US) 1996-04-17 EP disclosed
EP-0684830-A1 INHIBITORS OF THROMBOSIS CORVAS INTERNATIONAL, INC. (US) 1995-12-06 EP disclosed
EP-0627929-A4 INHIBITORS OF THROMBOSIS. CORVAS INT INC (US) 1995-07-12 EP disclosed
EP-0627929-A1 INHIBITORS OF THROMBOSIS CORVAS INTERNATIONAL, INC. (US) 1994-12-14 EP disclosed
WO-1994017817-A1 INHIBITORS OF THROMBOSIS CORVAS INTERNATIONAL, INC. (US) 1994-08-18 WO disclosed