Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515800 | 0.77 | PTGS1 (0.52) | GSK3AGSK3BRAB9ACYP2C19MGLL | |
| SCHEMBL255340 | 0.76 | MGLL (0.52) | GSK3AGSK3BRAB9ACYP2C19MGLL | |
| Hydrochloric Acid SCHEMBL28991159 | 0.75 | PTGS1 (0.50) | GSK3AGSK3BRAB9ACYP2C19MGLL | |
| SCHEMBL11955666 | 0.75 | GSK3A (0.55) | GSK3AGSK3BRAB9ACYP2C19MGLL | |
| SCHEMBL28353956 | 0.75 | GSK3A (0.50) | GSK3AGSK3BRAB9ACYP2C19MGLL | |
| SCHEMBL8010430 | 0.75 | GSK3A (0.50) | GSK3AGSK3BRAB9ACYP2C19MGLL | |
| SCHEMBL8738193 | 0.75 | GSK3A (0.46) | GSK3AGSK3BRAB9ACYP2C19MGLL | |
| SCHEMBL1704532 | 0.75 | MGLL (0.62) | GSK3AGSK3BRAB9ACYP2C19MGLL | |
| SCHEMBL29995038 | 0.73 | GSK3A (0.48) | GSK3AGSK3BRAB9ACYP2C19MGLL | |
| SCHEMBL1103791 | 0.73 | GSK3A (0.48) | GSK3AGSK3BRAB9ACYP2C19MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067221-A1 | AURISTATIN DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF | 上海齐鲁制药研究中心有限公司 | 2025-04-03 | — | — | WO | disclosed |
| WO-2024020164-A2 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | FIREFLY BIO, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| US-20230038373-A1 | STABILE CONJUGATE | GLYKOS BIOMEDICAL OY (FI) | 2023-02-09 | — | — | US | disclosed |
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |
| CN-113087650-A | Preparation method of 2-maleimidoacetic acid N-hydroxysuccinimide ester | 苏州昊帆生物股份有限公司 | 2021-07-09 | — | — | CN | disclosed |
| WO-2021110860-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2021-06-10 | — | — | WO | disclosed |
| CN-105669855-B | A kind of 18Method for rapidly marking Cys-Annexin V by using F and application thereof | 江苏省原子医学研究所 | 2020-02-11 | — | — | CN | disclosed |
| WO-2017060322-A2 | PTEFB-INHIBITOR-ADC | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | WO | disclosed |
| CN-105669855-A | Method for rapidly marking Cys-Annexin V through <18>F and application of method | 江苏省原子医学研究所 | 2016-06-15 | — | — | CN | disclosed |
| EP-2668039-B1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2015-06-03 | — | — | EP | disclosed |
| EP-0742903-B1 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | ROCHE DIAGNOSTICS CORP (US) | 2002-01-16 | — | — | EP | disclosed |
| EP-0429611-B1 | AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS | ROCHE DIAGNOSTICS GMBH (DE) | 2001-02-28 | — | — | EP | disclosed |
| EP-0742903-A4 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | ROCHE DIAGNOSTICS CORP (US) | 2000-04-05 | — | — | EP | disclosed |
| US-5798276-A | DETECTING COMPLEMENTARY MEMBER OF SPECIFIC BINDING PAIR USING FLUORESCENT CONJUGATE | MOLECULAR PROBES, INC. (US) | 1998-08-25 | — | — | US | disclosed |
| US-5595741-A | Aminoalkylmaleimides and hapten and antigen derivatives derived therefrom as well as conjugates with peptides or proteins | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-21 | — | — | US | disclosed |
| EP-0742903-A1 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | BOEHRINGER MANNHEIM CORPORATION (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5525474-A | IMMUNOASSAY; LINKING THE HAPTENIC DRUG VIA ITS MALEIMIDE MOIETY AND A SULFHYDRYL BRIDGE TO AN IMMUNOGENIC CARRIER TO STIMULATE ANTIBODIES | BOEHRINGER MANNHEIM CORPORATION (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1995020763-A1 | PIPERIDINE ANALOGS AND CONJUGATES OF PROCAINAMIDE AND NAPA | BOEHRINGER MANNHEIM CORPORATION (US) | 1995-08-03 | — | — | WO | disclosed |
| EP-0429611-A1 | AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS | Roche Diagnostics GmbH (DE) | 1991-06-05 | — | — | EP | disclosed |
| WO-1990015798-A1 | AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230038373-A1 | STABILE CONJUGATE | CD2, TTL, DDOST | GSK3A 3746/4885GSK3B 3998/4885RAB9A 998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.