Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166452 | 1.00 | ALOX5 (0.40) | ALOX5MAPTTP53CYP3A4MEN1 | |
| SCHEMBL3263073 | 0.83 | GABRA1 (0.32) | ESR1 | |
| SCHEMBL3263070 | 0.83 | GABRA1 (0.32) | ESR1 | |
| SCHEMBL13420955 | 0.78 | GABRA1 (0.33) | — | |
| SCHEMBL7693709 | 0.77 | ALDH1A1 (0.45) | ALOX5MAPTTP53CYP3A4MEN1 | |
| SCHEMBL7693706 | 0.77 | ALDH1A1 (0.45) | ALOX5MAPTTP53CYP3A4MEN1 | |
| SCHEMBL7171637 | 0.77 | PDE4A (0.44) | MAPTALDH1A1EGFR | |
| SCHEMBL7172589 | 0.76 | ALDH1A1 (0.39) | MAPTCYP3A4ALDH1A1NR5A1HTR1A | |
| SCHEMBL7172591 | 0.76 | ALDH1A1 (0.39) | MAPTCYP3A4ALDH1A1NR5A1HTR1A | |
| SCHEMBL7172091 | 0.75 | THRA (0.42) | MAPTESR1ALDH1A1LMNACYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569504-B1 | Dimers of LC-like compounds in which the monomers are linked to each other through a high birefringence moiety (dimerization linker) | DISPLAYTECH, INC. | 2003-05-27 | — | — | US | disclosed |
| US-6139771-A | USEFUL IN ELECTOOPTICAL AND NON-LINEAR OPTICAL APPLICATIONS | DISPLAYTECH, INC. (US) | 2000-10-31 | — | — | US | disclosed |