Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716667 | 1.00 | KDM5A (0.37) | KDM5AKDM2BKDM5BENPP2ATXN2 | |
| SCHEMBL697902 | 0.94 | NPSR1 (0.42) | FFAR1NPSR1MEN1KMT2AKDM4E | |
| SCHEMBL697860 | 0.91 | FFAR1 (0.35) | FFAR1NPC1MAPTRAB9AGRIN2B | |
| SCHEMBL697730 | 0.89 | GRM5 (0.41) | FFAR1TP53HPGD | |
| SCHEMBL696991 | 0.89 | L3MBTL1 (0.40) | FFAR1MAPTRAB9AGRIN2BLMNA | |
| SCHEMBL698928 | 0.89 | MAOA (0.35) | KDM5AKDM5BFFAR1KMT2AKDM4E | |
| SCHEMBL702018 | 0.88 | FFAR1 (0.35) | ENPP2FFAR1MEN1KMT2AKDM4E | |
| SCHEMBL698178 | 0.88 | SLC22A12 (0.35) | FFAR1NPSR1NPC1TP53MAPT | |
| SCHEMBL703335 | 0.87 | GRIN2B (0.42) | FFAR1NPSR1MEN1KMT2AKDM4E | |
| SCHEMBL697165 | 0.87 | GRIN2B (0.42) | FFAR1KDM4EMAPTHPGDGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |