Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PRCP | P42785 | 3/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917364 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAAPRCPSLC22A1 | |
| SCHEMBL9533144 | 0.76 | PRCP (0.59) | ALDH1A1KDM4EGAAPRCPSLC22A1 | |
| SCHEMBL918901 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAPRCPSLC22A1 | |
| SCHEMBL27985631 | 0.74 | PRCP (0.60) | ALDH1A1KDM4EGAAPRCPSLC22A1 | |
| SCHEMBL6429588 | 0.73 | PRCP (0.59) | ALDH1A1KDM4EGAAPRCPSLC22A1 | |
| Ammonia Solution, Strong SCHEMBL28831335 | 0.72 | PRCP (0.57) | ALDH1A1KDM4EGAAPRCPSLC22A1 | |
| SCHEMBL4340398 | 0.71 | PRCP (0.58) | ALDH1A1KDM4EGAAPRCPSLC22A1 | |
| SCHEMBL1009943 | 0.71 | PRCP (0.64) | ALDH1A1KDM4EGAAPRCPSLC22A1 | |
| SCHEMBL3245038 | 0.70 | KDM6B (0.38) | ALDH1A1KDM4EGAAOPRM1OPRK1 | |
| SCHEMBL330217 | 0.70 | PRCP (0.62) | ALDH1A1KDM4EGAAPRCPSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562836-B1 | Islet amyloid polypeptide (IAPP) is known to be capable of forming fibrils which are deposited in the pancreas of patients wtih type II diabetes | QUEEN'S UNIVERSITY OF KINGSTON (CA) | 2003-05-13 | — | — | US | claimed |