Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28569241 | 0.81 | ALDH1A1 (0.41) | NFKB1ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29134221 | 0.80 | NFKB1 (0.58) | NFKB1ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10382992 | 0.75 | RAB9A (0.44) | ALDH1A1SMN1; SMN2RAB9ANPC1TDP1 | |
| SCHEMBL28563944 | 0.73 | TDP1 (0.52) | NFKB1ALDH1A1RAB9ATDP1L3MBTL1 | |
| SCHEMBL22135293 | 0.68 | CYP3A4 (0.41) | ALDH1A1CYP2C19MAPT | |
| SCHEMBL29134257 | 0.66 | ALDH1A1 (0.56) | NFKB1ALDH1A1RAB9ANPC1CYP1A2 | |
| SCHEMBL10592821 | 0.66 | RAD52 (0.54) | ALDH1A1SMN1; SMN2RAB9ACYP1A2CYP2C9 | |
| SCHEMBL6532650 | 0.66 | AURKA (0.52) | ALDH1A1KMT2ACDK2CDK4MEN1 | |
| SCHEMBL609197 | 0.66 | BCL6 (0.57) | NFKB1ALDH1A1RAB9ANPC1CYP1A2 | |
| SCHEMBL5186527 | 0.65 | APP (0.38) | SMN1; SMN2RAB9AKMT2AMAPTCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6554037-B2 | Of an ethylene oxide-propylene oxide fatty alcohol adduct and an alkali metal salt of an alkylsulphonic or alkylsulphuric acid; protection of sidewalls against visible effects of migration of antioxidants and antiozonants | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2003-04-29 | — | — | US | claimed |
| US-20010051677-A1 | Of an ethylene oxide-propylene oxide fatty alcohol adduct and an alkali metal salt of an alkylsulphonic or alkylsulphuric acid; protection of sidewalls against visible effects of migration of antioxidants and antiozonants | MICHELIN RECHERCHE ET TECHNIQUE S.A. | 2001-12-13 | — | — | US | claimed |