Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3266022 | 0.79 | NPC1 (0.32) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7164718 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL7164815 | 0.77 | ALOX5 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7166917 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL7161910 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7163942 | 0.75 | WDR5 (0.30) | — | |
| Hydrochloric Acid SCHEMBL3124487 | 0.73 | NPC1 (0.49) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL3266023 | 0.72 | NPC1 (0.34) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7166639 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL7168530 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559234-B1 | Firstly provides a novel olefin/styrene/ diene type cross-copolymer having excellent physical properties and mechanical properties, and a novel, efficient and economically excellent process for its production. It provides an efficient | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2003-05-06 | — | — | US | disclosed |