Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20835448 | 1.00 | RAB9A (0.51) | RAB9AALDH1A1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL2584740 | 0.86 | LMNA (0.53) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL22040222 | 0.86 | NR3C2 (0.43) | RAB9AALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL3625341 | 0.86 | LMNA (0.53) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL13311119 | 0.86 | MAPT (0.50) | ALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL483661 | 0.86 | MAPT (0.50) | ALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL5153442 | 0.84 | TSHR (0.43) | RAB9AALDH1A1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL2586557 | 0.84 | TRPM8 (0.46) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1HSD17B10 | |
| SCHEMBL2584512 | 0.84 | TRPM8 (0.46) | RAB9AALDH1A1KDM4ETSHRATM | |
| SCHEMBL22546653 | 0.84 | DGAT2 (0.44) | RAB9AALDH1A1SMN1; SMN2L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033310-A1 | MODULATORS OF REV-ERB | KAMENECKA THEODORE MARK (US) | 2013-03-07 | — | — | WO | disclosed |
| EP-1083897-A4 | HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-1083897-A1 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062513-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 1999-12-09 | — | — | WO | disclosed |