Sugi Predict

Sugi Predict / Compounds / SCHEMBL29358985

SCHEMBL29358985

SCHEMBL29358985

CO/C=C(/C(=O)OC)c1ccccc1COc1ccc(Br)cn1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ GABRA5 P31644 2/20 0.39
▸ LMNA P02545 1/20 0.39
▸ ATM Q13315 1/20 0.38
▸ NPC1 O15118 3/20 0.36
▸ RAB9A P51151 3/20 0.36
▸ TP53 P04637 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ HIF1A Q16665 2/20 0.36
▸ CD274 Q9NZQ7 1/20 0.36
▸ PKM P14618 2/20 0.35
▸ GAA P10253 1/20 0.35
▸ NFKB1 P19838 1/20 0.35
▸ NFKB2 Q00653 1/20 0.35
▸ RELA Q04206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31289594 1.00 SMN1; SMN2 (0.39) SMN1; SMN2KDM4EGABRA5LMNAATM
SCHEMBL203004 1.00 SMN1; SMN2 (0.39) SMN1; SMN2KDM4EGABRA5LMNAATM
SCHEMBL8338895 0.90 GABRA5 (0.42) SMN1; SMN2KDM4EGABRA5LMNANPC1
SCHEMBL2851872 0.90 GABRA5 (0.42) SMN1; SMN2KDM4EGABRA5LMNANPC1
SCHEMBL2851880 0.90 GABRA5 (0.42) SMN1; SMN2KDM4EGABRA5LMNANPC1
SCHEMBL26935195 0.85 PKM (0.37) GABRA5HIF1ACD274PKM
SCHEMBL7171950 0.84 MAPK1 (0.41) KDM4EMAPK1HIF1A
SCHEMBL7171946 0.84 MAPK1 (0.41) KDM4EMAPK1HIF1A
SCHEMBL9004438 0.83 ATM (0.34) SMN1; SMN2KDM4ELMNAATMNPC1
SCHEMBL11937285 0.83 CD274 (0.38) GABRA5HIF1ACD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616081-B2 High precision greenhouse seed and seedling treatment SYNGENTA CROP PROTECTION AG (CH) 2026-05-05 — — US disclosed
US-12376512-B2 Precision treatment and sowing or planting method and device SYNGENTA CROP PROTECTION AG (CH) 2025-08-05 — — US disclosed
WO-2025132417-A1 GRANULAR MATERIAL COMPRISING A CARBOXYMETHYLCELLULOSE BINDER OMYA INTERNATIONAL AG (CH) 2025-06-26 — — WO disclosed
US-12262710-B2 Fungicidal compounds SYNGENTA CROP PROTECTION AG (CH) 2025-04-01 — — US disclosed
CN-119684124-A Fungicidal compounds 先正达农作物保护股份公司 2025-03-25 — — CN disclosed
EP-4017244-B1 APPARATUS AND METHOD FOR REDUCING DUST DEVELOPMENT IN PRECISION DRILL SOWING SYNGENTA CROP PROTECTION AG (CH) 2025-03-12 — — EP disclosed
US-12213396-B2 Apparatus and method for converting existing sowing equipment SYNGENTA CROP PROTECTION AG (CH) 2025-02-04 — — US disclosed
CN-113646295-B Fungicidal compounds 先正达农作物保护股份公司 2024-11-15 — — CN disclosed
EP-3848364-B1 MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION SYNGENTA CROP PROTECTION AG (CH) 2024-10-23 — — EP disclosed
US-12043600-B2 Microbiocidal compounds SYNGENTA CROP PROTECTION AG (CH) 2024-07-23 — — US disclosed
CN-114269145-A Apparatus and method for converting an existing sowing apparatus 先正达参股股份有限公司 2022-04-01 — — CN disclosed
CN-114258261-A Apparatus and method for reducing dust development in precision drilling 先正达参股股份有限公司 2022-03-29 — — CN disclosed
WO-2022058580-A1 MICROBIOCIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-03-24 — — WO disclosed
CN-108779109-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-03-11 — — CN disclosed
US-11266146-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-03-08 — — US disclosed
US-11259524-B2 Microbiocidal oxadiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-03-01 — — US disclosed
US-11241011-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-02-08 — — US disclosed
CN-108137570-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-01-28 — — CN disclosed
CN-108368098-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-01-28 — — CN disclosed
EP-3941898-A1 FUNGICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043600-B2 Microbiocidal compounds MPO, MSR1, PRF1 SMN1; SMN2 3579/4885KDM4E 2462/4885GABRA5 2323/4885
US-12616081-B2 High precision greenhouse seed and seedling treatment DCX, MYB, CROCC SMN1; SMN2 3133/4885KDM4E 4269/4885GABRA5 4663/4885
US-11241011-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 SMN1; SMN2 4749/4885KDM4E 1828/4885GABRA5 2965/4885
US-11266146-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 SMN1; SMN2 4749/4885KDM4E 1828/4885GABRA5 2965/4885
US-11259524-B2 Microbiocidal oxadiazole derivatives PRF1, NOX1, ARG1 SMN1; SMN2 3056/4885KDM4E 2601/4885GABRA5 2123/4885
US-12262710-B2 Fungicidal compounds CYP1B1, CYP51A1, CYP1A1 SMN1; SMN2 1500/4885KDM4E 852/4885GABRA5 767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.