Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750645 | 0.74 | CA2 (0.51) | CA2KDM4EPOLBALDH1A1HDAC3 | |
| SCHEMBL751883 | 0.74 | CA2 (0.51) | CA2KDM4EPOLBALDH1A1HDAC3 | |
| SCHEMBL8907294 | 0.71 | CA2 (0.49) | CA2KDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL16398871 | 0.71 | CA2 (0.56) | CA2KDM4EPOLBALDH1A1HDAC3 | |
| SCHEMBL777369 | 0.70 | CA2 (0.71) | CA2KDM4EPOLBALDH1A1HDAC3 | |
| SCHEMBL7752229 | 0.70 | KCNH2 (0.47) | CNR1KCNH2ADRA1ASLC6A3 | |
| SCHEMBL27911507 | 0.70 | MMP13 (0.37) | KDM4EPOLBALDH1A1KMT2A | |
| SCHEMBL3250020 | 0.70 | SRC (0.53) | CA2KDM4EPOLBALDH1A1TSHR | |
| SCHEMBL7171970 | 0.69 | CA2 (0.44) | CA2KDM4EALDH1A1KCNH2 | |
| SCHEMBL11758463 | 0.69 | CA2 (0.46) | CA2POLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576613-B1 | Arginine derivatives; monitoring plasminogen activator levels; inhibiting angiogenesis and tumor cell growth | CORVAS INTERNATIONAL, INC. | 2003-06-10 | — | — | US | disclosed |
| US-6432922-B1 | ANTITUMOR AGENTS; ANGIOGENESIS INHIBITORS | CORVAS INTERNATIONAL, INC. | 2002-08-13 | — | — | US | disclosed |