Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10895943 | 0.75 | THRB (0.41) | THRBTDP1AKR1B1CYP2C19CYP2C9 | |
| SCHEMBL9346852 | 0.72 | THRB (0.38) | THRBTDP1AKR1B1CYP2C19CYP2C9 | |
| SCHEMBL524491 | 0.71 | THRB (0.61) | THRBTDP1AKR1B1CYP2C19CYP2C9 | |
| SCHEMBL5886685 | 0.71 | THRB (0.38) | THRBTDP1AKR1B1CYP2C19CYP2C9 | |
| SCHEMBL8607562 | 0.71 | CYP2C19 (0.37) | THRBTDP1AKR1B1CYP2C19CYP2C9 | |
| SCHEMBL9341765 | 0.71 | THRB (0.37) | THRBTDP1AKR1B1CYP2C19CYP2C9 | |
| SCHEMBL4633534 | 0.70 | LMNA (0.41) | THRBTDP1CYP2C19CYP2C9CYP3A4 | |
| Bromide SCHEMBL27764709 | 0.69 | THRB (0.59) | THRBTDP1AKR1B1CYP2C19CYP2C9 | |
| SCHEMBL8051377 | 0.68 | CYP2C19 (0.36) | THRBTDP1AKR1B1CYP2C19CYP2C9 | |
| SCHEMBL727644 | 0.68 | CFTR (0.40) | TDP1AKR1B1CYP2C19CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026146-B1 | A method for producing purified phenylenedioxydiacetic acids | SUMITOMO CHEMICAL CO (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6316666-B1 | PRECIPITATION BY MIXING ALKALINE AQUEOUS SOLUTION OF CRUDE PHENYLENEDIOXYDIACETIC ACID WITH MINERAL ACID; ETHERIFICATION | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-1026146-A2 | A method for producing purified phenylenedioxydiacetic acids | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-08-09 | — | — | EP | disclosed |