SCHEMBL7173266

SCHEMBL7173266

NCCC[C@H]1Oc2ccc(C[C@H](NS(=O)(=O)c3cccc4ccccc34)C(=O)O)cc2NC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 5/20 0.41
ITGB3 P05106 4/20 0.40
ITGA2B P08514 3/20 0.40
PLAU P00749 3/20 0.40
TYMS P04818 2/20 0.40
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
F2 P00734 3/20 0.39
PLG P00747 3/20 0.39
ITGAV P06756 2/20 0.39
ST14 Q9Y5Y6 2/20 0.39
ITGB1 P05556 1/20 0.39
ITGA4 P13612 1/20 0.39
NPY5R Q15761 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7163795 0.90 F10 (0.41) F10ITGB3ITGA2BPLAUTYMS
SCHEMBL7168938 0.88 ITGB3 (0.44) ITGB3ITGA2BITGAVALDH1A1
SCHEMBL7159780 0.86 CASP1 (0.43) F10ITGB3ITGA2BPLAUTYMS
SCHEMBL7166473 0.83 ITGB3 (0.55) ITGB3ITGA2BSLC1A3SLC1A2SLC1A1
SCHEMBL7159817 0.82 ITGB3 (0.45) F10ITGB3ITGA2BPLAUTYMS
SCHEMBL7167819 0.81 USP2 (0.39) ITGB3ITGA2BITGAVHSD17B10
SCHEMBL7365624 0.80 CASP1 (0.41) F10PLAUTYMSPLGNPY5R
SCHEMBL7163689 0.80 ITGB3 (0.48) ITGB3ITGA2BITGAVALDH1A1CYP3A4
SCHEMBL7168506 0.79 ITGB3 (0.54) ITGB3ITGA2BITGAVHSD17B10
SCHEMBL7168903 0.78 ITGB3 (0.43) ITGB3ITGA2BITGAVITGB1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022125444-A1 APPARATUS AND METHOD FOR PROTECTING AGAINST MICROBIAL HAZARDS GMR Labs, LLC (US) 2022-06-16 WO claimed
US-20220174945-A1 APPARATUS AND METHOD FOR PROTECTING AGAINST MICROBIAL HAZARDS GMR Labs, LLC (US) 2022-06-09 US claimed
US-6554928-B2 A polystyrene based thermoplastic block copolymer and a thermoplastic modifier miscible with the block copolymer and having glass transition temperature => 170 degree C. used as binder in a gas generating material in an air bag TRW INC. 2003-04-29 US claimed
US-20020096234-A1 Binder for a gas generating material TRW INC. 2002-07-25 US claimed
US-11906866-B2 Electrochromic films and methods of forming and using GENTEX CORPORATION (US) 2024-02-20 US disclosed
US-11709407-B2 Immobilized buffers in electroactive devices GENTEX CORPORATION (US) 2023-07-25 US disclosed
WO-2022125444-A1 APPARATUS AND METHOD FOR PROTECTING AGAINST MICROBIAL HAZARDS GMR Labs, LLC (US) 2022-06-16 WO disclosed
US-20220174945-A1 APPARATUS AND METHOD FOR PROTECTING AGAINST MICROBIAL HAZARDS GMR Labs, LLC (US) 2022-06-09 US disclosed
EP-3953762-A1 LOW DIMERIZING VIOLOGEN ELECTROCHROMIC COMPOUNDS AND DEVICES GENTEX CORPORATION (US) 2022-02-16 EP disclosed
US-20210318584-A9 ELECTROCHROMIC COMPOUNDS AND DEVICES GENTEX CORPORATION 2021-10-14 US disclosed
US-20210255517-A1 IMMOBILIZED BUFFERS IN ELECTROACTIVE DEVICES GENTEX CORPORATION (US) 2021-08-19 US disclosed
US-20200409225-A1 ELECTROCHROMIC FILMS AND METHODS OF FORMING AND USING GENTEX CORPORATION 2020-12-31 US disclosed
WO-2020208529-A1 LOW DIMERIZING VIOLOGEN ELECTROCHROMIC COMPOUNDS AND DEVICES GENTEX CORPORATION (US) 2020-10-15 WO disclosed
US-20200326602-A1 LOW DIMERIZING VIOLOGEN ELECTROCHROMIC COMPOUNDS AND DEVICES GENTEX CORPORATION 2020-10-15 US disclosed
US-9455177-B1 Contact hole formation methods DOW GLOBAL TECHNOLOGIES LLC (US) 2016-09-27 US disclosed
US-6559144-B2 Integrin inhibitors used to treat circulatory disorders, for thrombosis, myocardial infarct, coronary heart disease, arteriosclerosis, osteoporosis, pathological processes maintained or propagated by angiogenesis and tumor therapy MERCK PATENT GESELLSCHAFT MIT (DE) 2003-05-06 US disclosed
US-6554928-B2 A polystyrene based thermoplastic block copolymer and a thermoplastic modifier miscible with the block copolymer and having glass transition temperature => 170 degree C. used as binder in a gas generating material in an air bag TRW INC. 2003-04-29 US disclosed
EP-0964856-B1 BICYCLIC AMINO ACIDS MERCK PATENT GMBH (DE) 2002-10-09 EP disclosed
US-20020096234-A1 Binder for a gas generating material TRW INC. 2002-07-25 US disclosed
US-20010021709-A1 Bicyclic amino acids MERCK PATENT GESELLSCHAFT MIT BESCHRANKT PATENTS (DE) 2001-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010021709-A1 Bicyclic amino acids ITGA1, ITGB1, ITGB2 F10 126/4885ITGB3 5/4885ITGA2B 14/4885
US-20210318584-A9 ELECTROCHROMIC COMPOUNDS AND DEVICES KCND2, KCNH2, KCNC1 F10 2947/4885ITGB3 382/4885ITGA2B 295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.